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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
2,4,6-TRINITROTOLUENE | No effect | Spermatozoa counts/motility | M | Adult | 60 | 0, 3, 15, 25, 35, 45 mg/kg/d | TOX-Non-Repro-Sublethal - cellular/biochemical effects | Daily doses through mortality | Oral gavage | Toxicity Factor Datasets | |
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE | 72 mg/kg [49-106 (95% CI)] | LD50 | M | Adult | U.S. Army Center for Health Promotion and Preventive Medicine | 44 | 0, 20-200 mg/kg | TOX-MORT - toxicity benchmarks | Single dose | Oral gavage | Toxicity Factor Datasets |
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE | 88 mg/kg [65-119 (95% CI)] | LD50 | F | Adult | U.S. Army Center for Health Promotion and Preventive Medicine | 44 | 0, 20-200 mg/kg | TOX-MORT - toxicity benchmarks | Single dose | Oral gavage | Toxicity Factor Datasets |
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE | 3.25 d | Mean days of survival | M | Adult | U.S. Army Center for Health Promotion and Preventive Medicine | 42 | 0, 10, 20, 25, 30, 45, 60 mg/kg/d | TOX-MORT - toxicity benchmarks | 14 d | Oral gavage | Toxicity Factor Datasets |
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE | Decreased to near zero comp to control | Cricket consumption | M | Adult | U.S. Army Center for Health Promotion and Preventive Medicine | 42 | 0, 10, 20, 25, 30, 45, 60 mg/kg/d | TOX-Non-Repro-Sublethal - whole animal | 14 d | Oral gavage | Toxicity Factor Datasets |
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE | No effect | Body weight change | M | Adult | U.S. Army Center for Health Promotion and Preventive Medicine | 42 | 0, 10, 20, 25, 30, 45, 60 mg/kg/d | TOX-Non-Repro-Sublethal - whole animal | 14 d | Oral gavage | Toxicity Factor Datasets |
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE | No effect | Hematological chemistry | M | Adult | U.S. Army Center for Health Promotion and Preventive Medicine | 42 | 0, 10, 20, 25, 30, 45, 60 mg/kg/d | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 14 d | Oral gavage | Toxicity Factor Datasets |
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE | Decreased | Cricket consumption | M | Adult | U.S. Army Center for Health Promotion and Preventive Medicine | 60 | 0, 1, 2.5, 5, 8, 11 mg/kg/d | TOX-Non-Repro-Sublethal - whole animal | 60 d | Oral gavage | Toxicity Factor Datasets |
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE | Decreased | Body weight change | M | Adult | U.S. Army Center for Health Promotion and Preventive Medicine | 60 | 0, 1, 2.5, 5, 8, 11 mg/kg/d | TOX-Non-Repro-Sublethal - whole animal | 60 d | Oral gavage | Toxicity Factor Datasets |
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE | No effect | Brain weight | M | Adult | U.S. Army Center for Health Promotion and Preventive Medicine | 60 | 0, 1, 2.5, 5, 8, 11 mg/kg/d | TOX-Non-Repro-Sublethal - organ/system effects | 60 d | Oral gavage | Toxicity Factor Datasets |
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE | Increased | Liver weight | M | Adult | U.S. Army Center for Health Promotion and Preventive Medicine | 60 | 0, 1, 2.5, 5, 8, 11 mg/kg/d | TOX-Non-Repro-Sublethal - organ/system effects | 60 d | Oral gavage | Toxicity Factor Datasets |
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE | Increased | Kidney weight | M | Adult | U.S. Army Center for Health Promotion and Preventive Medicine | 60 | 0, 1, 2.5, 5, 8, 11 mg/kg/d | TOX-Non-Repro-Sublethal - organ/system effects | 60 d | Oral gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE | No effect | Spermatozoa counts/motility | M | Adult | U.S. Army Center for Health Promotion and Preventive Medicine | 60 | 0, 1, 2.5, 5, 8, 11 mg/kg/d | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 60 d | Oral gavage | Toxicity Factor Datasets |
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE | No effect | Testosterone concentation | M | Adult | U.S. Army Center for Health Promotion and Preventive Medicine | 60 | 0, 1, 2.5, 5, 8, 11 mg/kg/d | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 60 d | Oral gavage | Toxicity Factor Datasets |
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE | 8.45 µg/g | Brain concentration | M | Adult | U.S. Army Center for Health Promotion and Preventive Medicine | 60 | 0, 1, 2.5, 5, 8, 11 mg/kg/d | TOX-EXP IND - accumulation | 60 d | Oral gavage | Toxicity Factor Datasets |
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE | 27.75 µg/g | Brain concentration | M | Adult | U.S. Army Center for Health Promotion and Preventive Medicine | 42 | 0, 1, 2.5, 5, 8, 11 mg/kg/d | TOX-EXP IND - accumulation | Single dose | Oral gavage | Toxicity Factor Datasets |
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE | 19.33 d | Mean days of survival | M | Adult | U.S. Army Center for Health Promotion and Preventive Medicine | 60 | 0, 1, 2.5, 5, 8, 11 mg/kg/d | TOX-MORT - toxicity benchmarks | 60 d | Oral gavage | Toxicity Factor Datasets |
2-AMINO-4,6-DINITROTOLUENE | 1406 [947-2087 (95% CI)] | LD50 | M | Adult | 60 | 0, 200-3175 mg/kg | TOX-MORT - toxicity benchmarks | Single dose | Oral gavage | Toxicity Factor Datasets | |
2-AMINO-4,6-DINITROTOLUENE | 1867 [1076-3237 (95%CI)] | LD50 | F | Adult | 60 | 0, 200-5000 mg/kd | TOX-MORT - toxicity benchmarks | Single dose | Oral gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
2-AMINO-4,6-DINITROTOLUENE | 9.3 d | Days of survival | M | Adult | 60 | 0, 15, 24, 38, 60, 95, 150 mg/kg/d | TOX-MORT - toxicity benchmarks | 14 d | Oral gavage | Toxicity Factor Datasets |
2-AMINO-4,6-DINITROTOLUENE | 9.9 d | Days of survival | F | Adult | 60 | 0, 15, 24, 38, 60, 95, 150 mg/kg/d | TOX-MORT - toxicity benchmarks | 14 d | Oral gavage | Toxicity Factor Datasets |
2-AMINO-4,6-DINITROTOLUENE | Decreased | Days of survival | M | Adult | 42 | 0, 15, 24, 38, 60, 95, 150 mg/kg/d | TOX-MORT - toxicity benchmarks | 14 d | Oral gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
2-AMINO-4,6-DINITROTOLUENE | Decreased | Cricket consumption | M | Adult | 42 | 0, 15, 24, 38, 60, 95, 150 mg/kg/d | TOX-Non-Repro-Sublethal - whole animal | 14 d | Oral gavage | Toxicity Factor Datasets | |
2-AMINO-4,6-DINITROTOLUENE | Increased | Blood BUN | M | Adult | 42 | 0, 5, 15, 20, 25, 30 mg/kg/d | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 60 d | Oral gavage | Toxicity Factor Datasets | |
PHOSPHORIC ACID | No effect | Righting reflex, sprinting, prey capture | NR | Not Reported | Texas Tech University | 30 | 0, 1x, 2x label rate | TOX-Non-Repro-Sublethal - behavioral effects | Single dose | Toxicity Factor Datasets | |
DDE (4,4'-) | 7.76 ug/kg ww | Egg concentrations | Embryo | Fern Ridge Reservoir | 14 | NR | TOX-EXP IND - accumulation | Environmental contamination | Toxicity Factor Datasets | ||
OXYCHLORDANE | 1.27 µg/kg ww | Egg concentrations | Embryo | Fern Ridge Reservoir | 14 | NR | TOX-EXP IND - accumulation | Environmental contamination | Toxicity Factor Datasets | ||
TRANS-NONCHLOR | 0.90 µg/kg ww | Egg concentrations | Embryo | Fern Ridge Reservoir | 14 | NR | TOX-EXP IND - accumulation | Environmental contamination | Toxicity Factor Datasets | ||
MIREX | 0.36 µg/kg ww | Egg concentrations | Embryo | Fern Ridge Reservoir | 14 | NR | TOX-EXP IND - accumulation | Environmental contamination | Toxicity Factor Datasets | ||
DIELDRIN | 0.19 µg/kg ww | Egg concentrations | Embryo | Fern Ridge Reservoir | 14 | NR | TOX-EXP IND - accumulation | Environmental contamination | Toxicity Factor Datasets | ||
HEPTACHLOR EPOXIDE | 0.13 µg/kg ww | Egg concentrations | Embryo | Fern Ridge Reservoir | 14 | NR | TOX-EXP IND - accumulation | Environmental contamination | Toxicity Factor Datasets | ||
CIS-NONCHLOR | 0.08 µg/kg ww | Egg concentrations | Embryo | Fern Ridge Reservoir | 14 | NR | TOX-EXP IND - accumulation | Environmental contamination | Toxicity Factor Datasets | ||
PCB | Decreased | Plasma carotenoids µg/mL at pairing | M | Adult | Avian Science and Conservation Centre of McGill University | 49 | 7 mg/kg body mass /day | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 100 d | Dietary | Toxicity Factor Datasets |
PCB | Increased | Plasma carotenoids µg/mL 7 d post pairing | F | Adult | Avian Science and Conservation Centre of McGill University | 50 | 7 mg/kg body mass /day | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 100 d | Dietary | Toxicity Factor Datasets |
PCB | No effect | Plasma carotenoids µg/mL at pairing | M | Adult | Avian Science and Conservation Centre of McGill University | 49 | 7 mg/kg body mass /day | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 100 d | Dietary | Toxicity Factor Datasets |
PCB | No effect | Plasma carotenoids µg/mL 7 d post pairing | F | Adult | Avian Science and Conservation Centre of McGill University | 50 | 7 mg/kg body mass /day | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 100 d | Dietary | Toxicity Factor Datasets |
PCB | No effect | Plasma carotenoids µg/mL fledglings | B | Juvenile | Avian Science and Conservation Centre of McGill University | NR | in ovo, 7 mg/kg body mass /day parent diet | TOX-Non-Repro-Sublethal - cellular/biochemical effects | in ovo | Toxicity Factor Datasets | |
PCB | Increased | Coloration of ceres & lores at pairing | M | Adult | Avian Science and Conservation Centre of McGill University | 49 | 7 mg/kg body mass /day | TOX-Non-Repro-Sublethal - whole animal | 100 d | Dietary | Toxicity Factor Datasets |
PCB | No effect | Coloration of ceres & lores at pairing | F | Adult | Avian Science and Conservation Centre of McGill University | 50 | 7 mg/kg body mass /day | TOX-Non-Repro-Sublethal - whole animal | 100 d | Dietary | Toxicity Factor Datasets |
PCB | No effect | Coloration of ceres & lores 7 d post pairing | B | Adult | Avian Science and Conservation Centre of McGill University | 99 | TOX-Non-Repro-Sublethal - whole animal | 100 d | Dietary | Toxicity Factor Datasets |